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This course acquaints the senior student with techniques used in simple research problems. May be repeated for an additional three semester hours by those students having a definite project to complete. This course may be taken for Academic Distinction Credit. See Academic Distinction Program in this catalog.
Prerequisite: Student must have a minimum of 20 semester hours in chemistry and consent of the Department Chair.

Spectrophotometry, separation techniques and mass spectrometry are discussed. Specific topics include the computer's use in the modern laboratory, ultraviolet and visible absorption, atomic absorption, flame emission, and inductively coupled plasma spectroscopy, infrared absorption, and gas and liquid chromatography. Instruments for these techniques are used in the laboratory work. Four-hour laboratory. Fall.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2325, CHEM 2401, and CHEM 4448.

The chemistry of compounds containing metal ions is discussed. Emphasis in placed on the complexes of transition metals. The electronic configurations of these ions in various bonding environments are considered in interpreting their chemical and physical properties.
Prerequisite: CHEM 4367 and CHEM 4448.

Principles are stressed including the three laws of thermodynamics, thermochemistry and statistical thermodynamics. Applications of the principles to gases, solution, mixtures, solids and interfaces are given.
Prerequisite: CHEM 4448.

This course is adaptable to the needs and interests of the individual graduate student majoring in Chemistry. Modern developments in specific subdivisions of the field of chemistry are considered. It may be repeated for credit, provided the repetition is not in the same subdivisional field. The subdivisional fields offered are: analytical, biochemistry, environmental, inorganic, organic, and physical chemistry.
Prerequisite: Graduate standing in Chemistry.

Laboratory for CHEM 1305. Concurrent enrollment in CHEM 1305 is recommended.

Chemical phenomena, concepts and principles are explored within the context of the role of science and technology in society. A life-centered approach rather than a subject-centered one has been employed in the development of course curriculum. This course is specifically designed to satisfy the natural science core requirement of students who are not specializing in science. Concurrent enrollment in CHEM 1105 is recommended.

The elements and their compounds are considered from a non-technical standpoint with emphasis placed on more familiar materials. Two-hour laboratory. This course is for non-science majors.

An orientation in organic chemistry is given in the first part of the course to allow treatment of the chemistry of nutrition and other biochemical aspects given in the last part. Two-hour laboratory. This course is for non-science majors.
Prerequisite: CHEM 1406, CHEM 1411, or completion of a high school chemistry course.

The following topics are studied: chemical changes and laws governing them; nomenclature; introduction to thermodynamics; reactions involving oxygen, hydrogen, acids, bases, and salts; ionization; metathesis; the periodic table, and atomic and molecular structure. Three-hour laboratory. This course is for chemistry and other science majors. Fall, Spring, Summer I.
Prerequisite: Minimum grade of C in MATH 1410, MATH 1314, MATH 1324 or MATH 2384 or equivalent, or a minimum Math score of 23 on the ACT or 560 on the SAT (580 on new SAT) or equivalent.

Descriptive chemistry, gas laws, equilibria, kinetics, thermodynamics, electrochemistry, and oxidation-reduction reactions are presented. Three-hour laboratory. Fall, Spring, Summer II.
Prerequisite: A minimum grade of C in CHEM 1411.

Laboratory for CHEM 2323. Fall, Spring, Summer I.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, and prior credit for or concurrent enrollment in CHEM 2323.

Laboratory for CHEM 2325. Fall, Spring, Summer II.
Prerequisite: A minimum grade of C in CHEM 1411,CHEM 1412, CHEM 2123, CHEM 2323, and prior credit for or concurrent enrollment in CHEM 2325.

A study of chemical bonding and structure of organic molecules is made. Functional group reactions and syntheses are emphasized. Reaction mechanisms, nomenclature and isomerism are studied. Fall, Spring, Summer I.
Prerequisite: A minimum grade of C in CHEM 1411 and CHEM 1412.

The general plan of CHEM 2323 is continued. Fall, Spring, Summer II.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, and CHEM 2123.

The fundamental principles of quantitative analysis are emphasized. Acid-base, complexometric, precipitation, and redox titrations, solution equilibria and spectrophotometric analysis are discussed. Laboratory exercises involve all types of volumetric procedures and colorimetric analysis. Four-hour laboratory. Fall, Spring.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412.

This course is a study of the bioenergetics associated with the metabolic pathways and processes. The metabolism of carbohydrates, lipids, proteins, and nucleic acids; the interrelationship of the metabolic pathways; and the regulation of metabolism are emphasized. Spring.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125 and CHEM 3438.

Attention will be focused on early scientists, the times in which they worked, important aspects of their efforts, and how their research continues to impact us today. Lectures will occur in the geographical areas where their work took place. Odd years during the Spring/Summer I break.
Prerequisite: CHEM 1406 or CHEM 1411, junior standing, and permission of the instructor.

General principles of inorganic chemistry are presented with a descriptive and practical rather than mathematical approach. Periodic relationships of elements and bonding, reactions and synthesis of inorganic compounds, acid-base chemistry are studied. Fall.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323.

The chemical principles underlying the effects of air, water, and soil pollution are covered. Specific attention is paid to gas phase radical reactions, light absorption characteristics of atmospheric components, solution chemistry of fresh and salt water systems, and the mobility and chemistry of metal components of soil systems. Spring even years.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2401, CHEM 2323 and CHEM 2325 (or concurrent enrollment in CHEM 2325).

The chemistry and functions of carbohydrates, lipids, proteins, enzymes, nucleic acids and vitamins; enzyme kinetics; the processes of and mechanisms of digestion and absorption; and biological buffers are studied. Four-hour laboratory. Fall, Summer.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125.

A directed study for undergraduates. This course is designed to allow independent study by advanced students. Instruction is on an individual basis. Variable Credit (1-3).
Prerequisite: A minimum grade of C in CHEM 2325 and approval of department chair.

Students explore an identified area of chemistry not covered in detail by other upper-level courses. This course may be repeated for credit if the topics vary. Variable Credit (1 to 4).
Prerequisite: Approval of department chair.

Methods of searching the literature in chemistry are presented. Emphasis is placed on the use of Chemical Abstracts, Beilstein, chemical patent literature, journals, and reference collections in the several specialties of chemistry. Fall, Spring.
Prerequisite: Junior standing in chemistry.

This course will involve in-depth experiments that require the use of sophisticated synthetic and analytical procedures in the areas of organic, inorganic or analytical chemistry. Spring.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125, CHEM 2401, CHEM 4448, and CHEM 4440.

Students examine reactions, synthesis, and mechanisms of polymerization processes as well as molecular weight distributions and structure/property relationships of polymers.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325 and CHEM 2125.

Properties of atoms and ions, bonding theory and structure, acid-base theory, reactions of inorganic compounds, nonaqueous solvents, and coordination chemistry are studied. Emphasis is on the underlying theoretical concepts involved. Spring.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125, CHEM 4448.

This is a one semester course focused on surveying important aspects of chemistry to forensic inquiries. Focus will be on the validity of results. Techniques and methods for selecting proper techniques to answer various questions will be discussed. Spring.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125, CHEM 4440 and CHEM 4367 (or concurrent enrollment in CHEM 4367); MATH 1420.

Students covers the philosophy of modern instrumental methods used for environmental and industrial analyses. The topics to be covered may include quality control and quality assurance good laboratory practices, waste minimization and elimination, safe laboratory operation, ISO standards, EPA methodology, and statistical data analysis. Spring. Spring.
Prerequisite: A minimum grade of C in CHEM 2401, CHEM 2323 and CHEM 2325, and CHEM 3368.

An in-depth study of the sources of air pollution is made. Sampling procedures and the chemical analyses required for identification of pollutants are studied. Control methods for the restriction of air pollution are outlined. Four-hour laboratory. Spring odd years.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2401, CHEM 2323 and CHEM 2325.

This course is a survey of the spectroscopic and spectrometric methods for elucidation of structural information for chemical compounds with emphasis on the structural identification of unknowns. The methods of ultraviolet-visible spectrophotometry, Fourier-transform infrared spectroscopy, mass spectrometry, and both one- and two-dimensional nuclear magnetic resonance spectroscopy will be covered. Their relative strengths, complementary nature, and utility will be discussed. The focus will be the determination of chemical structures by spectroscopic/spectrometric methods. Spring even years. Spring even years.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125.

The foundations of thermodynamics and spectroscopic methods (radio-frequency, microwave, infrared, Raman, UV-visible, and X-ray) are developed from first principles with an atomistic point of view. Four-hour laboratory. Fall.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125, MATH 1420, MATH 1430 and one year of physics.

The developments of thermochemistry, phase diagrams, equilibria, and kinetics are traced from the statistical mechanics of quantum states to the macroscopic observations of thermodynamics. Four-hour laboratory. Spring.
Prerequisite: A minimum grade of C in CHEM 1411, CHEM 1412, CHEM 2323, CHEM 2123, CHEM 2325, CHEM 2125, CHEM 4448.

This course is intended to provide an avenue for selected graduate students to engage in independent studies. Registration is on an individual basis and is restricted to students in residence. Variable Credit (1-3).
Prerequisite: Approval of department chair.

Students will participate in the departmental seminar program. This participation will require the preparation and presentation of current research material in a format acceptable to the American Chemical Society.

This course consists of a study of the effect of structure upon reactivity of organic compounds. The qualitative and quantitative relationship of structure to acidity and basicity in organic chemistry is developed. In addition, reactive intermediates (carbocations, carbanions and free radicals) are studied.
Prerequisite: CHEM 2325, CHEM 2125.

Current models for mechanisms of organic reactions are discussed and applied. The mechanisms and applications of synthetically important reactions are also surveyed. Literature searching for less often utilized but historically important transformations are integral to the course. The methods of determining reaction mechanisms are surveyed along with applications to individual reactions.
Prerequisite: CHEM 2325, CHEM 2125.

Students learn to set up a conceptual and empirical framework for designing, validating, and using calibrated measurements of chemical abundance within the context of chemical nano sensing. Students employ this framework to examine instruments used to study, and sensors designed to make advantageous use of, nanoscale phenomena in diverse chemical sensing settings.

Theory and application of selected areas of spectroscopy commonly used in qualitative and quantitative analysis are covered. Topics include atomic and molecular spectroscopy, mass spectrometry, laser analytical methods, fluorescence, phosphorescence, and chemiluminescence and their application to environmental, atmospheric, and bioanalytical problems.
Prerequisite: CHEM 4440.

The chemical structure and the biological functions and controls of proteins are reviewed. Proteins to be considered include enzymes, transport proteins and structural proteins. Protein biosynthesis and recombinant DNA technology are also discussed.

Students examines biotransformations of drugs/toxins, mechanisms of drug interactions with biological systems, and selective toxicity. Students gain insight into the design of therapeutic agents and the destruction of harmful toxins/bacterial invaders in living systems. Attention is also given to how molecular structure is related to solubility and permeability and how to design systems for drug delivery within the human body.

Students examine organometallic chemistry through a detailed presentation of structure and bonding. In addition, students focus on these principles with in-depth discussions of organometallic reaction mechanisms, advances in catalysis, carbene complexes. metathesis reactions, application to organic synthesis, and cluster compounds.
Prerequisite: CHEM 4367.

Quantum theory and symmetry are studied in detail and applied to the interpretation and prediction of spectroscopic data. Infrared, Raman, and electronic spectroscopic methods are examined in depth.
Prerequisite: CHEM 4448 or departmental approval.

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